Golgi-localized MCW1 Mediates Manganese Homeostasis, Which Is Essential for Arabidopsis Growth

Plants require the micronutrient element manganese (Mn) for normal growth and development. Mn2+/H+ antiporters and Mn2+ transporters have been described and studied in the plasma membrane and organelle membranes of plant cells. However, the transport of manganese into the lumen of the Golgi remains poorly understood. Here we report the identification and characterization of a Golgi-localized potentialMn2+/H+ antiporter, MCW1, in Arabidopsis thaliana.

锰（Mn）是植物正常生长发育所必需的微量营养元素。目前已在植物细胞的质膜与细胞器膜中，对Mn²⁺/H⁺反向转运体及Mn²⁺转运蛋白进行了报道与研究。然而，锰向高尔基体囊腔的转运过程至今仍不甚明晰。本研究报道了拟南芥（Arabidopsis thaliana）中一个定位于高尔基体的潜在Mn²⁺/H⁺反向转运体MCW1的鉴定及其功能表征。