Determination of EC50 in VIM-2 lactamase through deep mutational scanning

The study aims to use deep mutational scanning methodology to determine the EC50 of ~5600 single amino acid variants of VIM-2 in parallel.本研究旨在运用深度突变扫描（deep mutational scanning）方法学，并行测定VIM-2的约5600种单氨基酸变异体的半最大效应浓度（EC50）。