meta_data
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<b>tblhctmeta.csv: Day and source of hematopoietic cell transplant (HCT) for 1,278 patients</b>PatientID: deidentified identifier of patientsTimepointOfTransplant: deidentified day of HCTHCTSource: hematopoietic cell sources for HCT patients (BM_unmodified: bone marrow; PBSC_unmodified: peripheral blood stem cells; TCD: T-cell depleted; cord: cord blood)Disease: disease of patientswbcPatientId, autoFmtPatientId, nejmPatientId: identifiers for the same patients if they were also included in another previous study (wbcPatientId: Schluter, J. et al. 2019. The gut microbiota influences circulatory immune cell dynamics in humans. <i>BioRxiv</i>; autoFmtPatientId: Taur, Y. et al. 2018. Reconstitution of the gut microbiota of antibiotic-treated patients by autologous fecal microbiota transplant. <i>Science Translational Medicine</i> 10(460); nejmPatientId: Peled, J.U. et al. 2020. Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation. <i>New England Journal of Medicine</i>, <i>382</i>(9), pp.822-834.)<br><b>tbldrug.csv: Timing and route of drug administration for 1,279 patients</b>PatientID: deidentified identifier of patientsStartTimepoint: deidentified day when drug administration startedStopTimepoint: deidentified day when drug administration stopped (including the day)Factor: name of the drugCategory: category of the drugRoute: route of drug administration<br>StartDayRelativeToNearestHCT/StopDayRelativeToNearestHCT: start/stop day of the drug administration relative to the nearest day of bone marrow transplant<br><b>tblInfectionsCidPapers.csv: Day of positive blood cultures for 426 patients </b>(include only microbes analyzed in<b> </b>1. Taur, Y., et al. 2012. Intestinal domination and the risk of bacteremia in patients undergoing allogeneic hematopoietic stem cell transplantation. <i>Clinical infectious diseases</i>, <i>55</i>(7), pp.905-914; 2. Stoma, I., et al. 2020. Compositional flux within the intestinal microbiota and risk for bloodstream infection with gram-negative bacteria. <i>Clinical Infectious Diseases</i>.)PatientID: deidentified identifier of patientsTimepoint: deidentified day of infectionInfectiousAgent: the bacteria causing infectionsDayRelativeToNearestHCT: day of infection relative to the nearest day of bone marrow transplant<br><b>tblwbc.csv: Daily measurements of white blood cells for 1,242 patients</b>PatientID: deidentified ID of patientsTimepoint: deidentified day of blood cell measurementBloodCellType: lymphocyte cells (Lymphocytes), neutrophil cells (Neutrophils), and total white blood cells (WBCtotal)Value: blood cell counts (unit: 1,000 cells/uL)<br>DayRelativeToNearestHCT: day of blood cell measurement relative to the nearest day of bone marrow transplant<br><br><b>tbltemperature.csv: </b>temperatures for 1,249 patientsPatientID: deidentified identifier of patientsTimepoint: deidentified day when patient temperature was measuredMaxTemperature: Maximum temperature (unit: Fahrenheit) recorded on that day for that patientDayRelativeToNearestHCT: day of temperature measurement relative to the nearest day of bone marrow transplant<br><br><b>tblVanA.csv</b>: Results of PCR detection for <i>vanA </i>gene for 7,547 samplesSampleID: stool sample identifier VanA: whether <i>vanA</i> gene is detected in the sample
<b>tblhctmeta.csv:1278例患者造血细胞移植(hematopoietic cell transplant, HCT)的时机与供源</b>
PatientID:患者去标识化标识符
TimepointOfTransplant:造血细胞移植的去标识化移植日
HCTSource:造血细胞移植患者的造血细胞来源(BM_unmodified:未修饰骨髓;PBSC_unmodified:未修饰外周血干细胞;TCD:T细胞清除型;cord:脐带血)
Disease:患者所患疾病
wbcPatientId, autoFmtPatientId, nejmPatientId:若患者同时纳入既往另一项研究,则为对应患者的标识符(wbcPatientId:Schluter, J. 等,2019年。肠道菌群影响人体循环免疫细胞动态。<i>BioRxiv</i>;autoFmtPatientId:Taur, Y. 等,2018年。自体粪便菌群移植重建抗生素治疗患者的肠道菌群。<i>Science Translational Medicine</i> 10(460);nejmPatientId:Peled, J.U. 等,2020年。菌群作为异基因造血细胞移植死亡率的预测因子。<i>New England Journal of Medicine</i>, <i>382</i>(9), pp.822-834.)
<b>tbldrug.csv:1279例患者的给药时机与给药途径</b>
PatientID:患者去标识化标识符
StartTimepoint:给药开始的去标识化日期
StopTimepoint:给药停止的去标识化日期(含停药当日)
Factor:药物名称
Category:药物类别
Route:给药途径
StartDayRelativeToNearestHCT/StopDayRelativeToNearestHCT:距最近一次骨髓移植的给药开始/停止日(即给药开始/停止日期与最近骨髓移植日的相对天数)
<b>tblInfectionsCidPapers.csv:426例患者的血培养阳性日期</b>
(仅纳入在1. Taur, Y. 等,2012年。肠道定植与异基因造血干细胞移植患者菌血症风险。<i>Clinical infectious diseases</i>, <i>55</i>(7), pp.905-914;2. Stoma, I. 等,2020年。肠道菌群组成动态与革兰阴性菌血流感染风险。<i>Clinical Infectious Diseases</i> 中分析过的微生物)
PatientID:患者去标识化标识符
Timepoint:感染发生的去标识化日期
InfectiousAgent:引发感染的病原菌
DayRelativeToNearestHCT:距最近一次骨髓移植的感染日(即感染日期与最近骨髓移植日的相对天数)
<b>tblwbc.csv:1242例患者的白细胞每日检测数据</b>
PatientID:患者去标识化标识符
Timepoint:血细胞检测的去标识化日期
BloodCellType:血细胞类型,包括淋巴细胞(Lymphocytes)、中性粒细胞(Neutrophils)及白细胞总数(WBCtotal)
Value:血细胞计数(单位:1000个细胞/微升)
DayRelativeToNearestHCT:距最近一次骨髓移植的血细胞检测日(即检测日期与最近骨髓移植日的相对天数)
<b>tbltemperature.csv:1249例患者的体温数据</b>
PatientID:患者去标识化标识符
Timepoint:患者体温测量的去标识化日期
MaxTemperature:该患者当日记录的最高体温(单位:华氏度)
DayRelativeToNearestHCT:距最近一次骨髓移植的体温测量日(即测量日期与最近骨髓移植日的相对天数)
<b>tblVanA.csv:7547份样本的<i>vanA</i>基因PCR检测结果</b>
SampleID:粪便样本标识符
VanA:样本中是否检出<i>vanA</i>基因
提供机构:
figshare
创建时间:
2020-03-22



