Metal-Free Oxidative Formation of Aryl Esters by Catalytic Coupling of Acyl and Sulfonyl Chlorides with Arylboronic Acids

A practical and efficient synthesis of aryl esters was developed through metal-free oxidation. This reaction employs stable and readily available acyl or sulfonyl chlorides and arylboronic acids as the starting materials and proceeds under mild reaction conditions without additional precious metal catalysts. This new strategy exhibits broad substrate tolerance and operational simplicity and gives diverse aryl esters in moderate to high yields.

本工作开发了一种无金属氧化介导的实用高效芳基酯（aryl esters）合成方法。该反应以稳定易得的酰氯（acyl chloride）或磺酰氯（sulfonyl chloride）与芳基硼酸（arylboronic acids）为起始原料，可在温和反应条件下进行，无需额外添加贵金属催化剂。这一新策略具备宽泛的底物耐受性与操作简便性，能够以中等至优异的收率得到结构多样的芳基酯产物。