Abnormal event-related delta, theta, and alpha coherence response using visual oddball paradigm in Parkinson’s disease associated with cognitive impairment

Parkinson’s disease (PD) is a common neurodegenerative disease characterized by number of motor and non-motor dysfunctions. EEG pattern is a predictive of cognitive function in PD. In the present study, we investigated intra-hemispheric event related coherence with different cognitive dysfunctions in PD during visual oddball paradigm.

帕金森病（Parkinson’s disease, PD）是一种常见的神经退行性疾病，以多种运动及非运动功能障碍为主要临床特征。脑电图（Electroencephalogram, EEG）模式可作为帕金森病患者认知功能的预测指标。本研究在视觉Oddball范式下，针对伴不同认知功能障碍的帕金森病患者，探究其半球内部的事件相关相干性。