Supplementary Table 2 from CHK2 Inhibition Provides a Strategy to Suppress Hematologic Toxicity from PARP Inhibitors

Count table and fold enrichment for screens performed with the CRISPR/Cas9 DNA repair gene library. Read counts and analysis of guide enrichment or depletion in cells treated with olaparib (40 nM or 2 µM) or an untreated control. We present guide counts in each condition, normalised counts and log fold changes.

本数据集包含基于CRISPR/Cas9 DNA修复基因文库开展的筛选实验的计数表格与倍数富集分析结果。数据集涵盖经奥拉帕尼（olaparib，浓度分别为40 nM或2 µM）处理的细胞与未处理对照组细胞中的测序读段计数、向导RNA（guide）富集或缺失情况的分析数据，并提供了各实验条件下的向导RNA计数、标准化计数以及对数折叠变化值。