Inositol in Preventing Colorectal Cancer in Patients With Colitis-Associated Dysplasia

This pilot, randomized phase I/II trial studies how well inositol works in preventing colorectal cancer in patients with abnormal cells (dysplasia) associated with inflammation of the colon (colitis). Patients with colitis-associated dysplasia may have an increased risk of developing colorectal cancer. Inositol is a vitamin-like substance that may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

本项随机化先导Ⅰ/Ⅱ期临床试验旨在评估肌醇(inositol)对伴结肠炎症（结肠炎）相关异常细胞（异型增生）患者的结直肠癌预防效果。伴结肠炎相关异型增生的患者，其罹患结直肠癌的风险有所升高。肌醇是一种类维生素物质，可通过阻断细胞生长所需的部分酶类，抑制肿瘤细胞增殖。