EA-8P

EA-8P investigates the impact of Lactobacillus paracasei treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing on the Ion Torrent NGS System. Analysis via Ion Reporter SW (16S) revealed shifts in microbial taxa dynamics over days 1, 3, and 6, shedding light on the potential of probiotics in modulating gut microbiota during C. difficile infection.
The identification of the sample EA-8P:
E: Denotes the strain ST-37 of Clostridioides difficile.
A: Represents timepoint 1, indicating sampling before C. difficile infection.
3: Refers to the specific mouse number under investigation.
P: Indicates the treatment administered, which in this case is Lactobacillus paracase

本数据集EA-8P旨在探究副干酪乳杆菌（Lactobacillus paracasei）干预对艰难梭菌（Clostridioides difficile）感染小鼠肠道菌群的影响。研究人员对感染后小鼠的粪便样本采用Invitrogen进行前处理，并通过Ion Torrent NGS系统完成测序。借助Ion Reporter SW（16S）开展数据分析后发现，在感染后的第1、3、6天，微生物类群的动态丰度发生显著改变，该研究为益生菌在艰难梭菌感染期间调控肠道菌群的潜在效用提供了实验依据。

样本EA-8P的命名规则如下：
E：代表艰难梭菌菌株ST-37；
A：指代采样时间节点1，即艰难梭菌感染前的采样时点；
3：代表本次研究中的特定小鼠编号；
P：表示所施加的干预措施，本研究中为副干酪乳杆菌（Lactobacillus paracasei）。