Gene expression profiles of induced pluripotent stem cells from centenarians

We established induced pluripotent stem cells (iPSC) from centrenarians by retroviral transduction of primary human fibroblasts. To show the similarity between 201B7 iPSC and 100-1 #16 iPSC (induced pluripotent stem cells from centenarian), this experiment was designed. Undifferentiated 201B7 iPSC, and 100-1 #16 iPSCs were collected. Then, they were applied in this experiment.

我们通过逆转录病毒转导原代人成纤维细胞，从百岁老人体内构建诱导多能干细胞（induced pluripotent stem cells, iPSC）。为验证201B7诱导多能干细胞与100-1 #16诱导多能干细胞（源自百岁老人的诱导多能干细胞）的相似性，本实验设计如下：收集未分化的201B7诱导多能干细胞与100-1 #16诱导多能干细胞，并将其应用于本实验。