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Additional file 4: of Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity

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Table S3. Associations between DNA methylation and splicing as observed in the iPS (a-g) and endoderm (h-n) single cells. Each table contains significant associations per sequence context per tissue. The cassette exon, P value (nominal and after multiple testing correction), effect size and effect direction are shown. a. C1 iPS. b. I1 ‘5 iPS. c. I1 ‘3 iPS. d. A iPS. e. I2 ‘5 iPS. f. I2 ‘3 iPS. g. C2 iPS. h. C1 endoderm. i. I1 ‘5 endoderm. j. I1 ‘3 endoderm. k. A endoderm. l. I2 ‘5 endoderm S. m. I2 ‘3 iPS. n. C2 endoderm. (XLSX 163 kb)

附表S3。本附表收录了在诱导多能干细胞(induced pluripotent stem cells,iPS)(a~g组)与内胚层细胞(h~n组)的单细胞中观测到的DNA甲基化与可变剪接关联结果。各表格均按组织与序列背景分类,列出其中的显著关联,涵盖盒式外显子、P值(名义P值与多重检验校正后P值)、效应量及效应方向。a. C1 iPS细胞;b. I1 5'端iPS细胞;c. I1 3'端iPS细胞;d. A iPS细胞;e. I2 5'端iPS细胞;f. I2 3'端iPS细胞;g. C2 iPS细胞;h. C1内胚层细胞;i. I1 5'端内胚层细胞;j. I1 3'端内胚层细胞;k. A内胚层细胞;l. I2 5'端内胚层S;m. I2 3'端iPS细胞;n. C2内胚层细胞。(XLSX 163 kb)
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figshare
创建时间:
2019-02-12
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