Structure of Beta-Klotho in Complex with FGF19 C-terminal peptide
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Structure of Beta-Klotho in Complex with FGF19 C-terminal peptide Descriptor: Beta-klotho, Fibroblast growth factor 19, Nanobody 30 Authors: Kuzina, E, Schlessinger, J, Lee, S. Deposit date: 2018-12-20 Release date: 2019-04-03 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (3.19 Å) Cite: Structures of ligand-occupied beta-Klotho complexes reveal a molecular mechanism underlying endocrine FGF specificity and activity. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
数据集标题:与FGF19 C端肽结合的β-klotho复合物结构 描述:本复合物组成包括β-klotho(Beta-Klotho)、成纤维细胞生长因子19(Fibroblast growth factor 19)以及纳米抗体30(Nanobody 30) 作者:库济娜(Kuzina, E)、施莱辛格(Schlessinger, J)、李(Lee, S.) 沉积日期:2018-12-20 发布日期:2019-04-03 最后修改日期:2024-10-30 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率3.19 Å 引用文献:《配体结合型β-klotho复合物的结构揭示了内分泌型成纤维细胞生长因子特异性与活性的分子机制》,Proc. Natl. Acad. Sci. U.S.A.,116卷,2019年




