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scRNA- and TCR-Seq of mouse T cells from WT and TIGIT KO mice at steady state and upon LCMV infection

ChEBI2025-09-14 更新2026-07-12 收录

单细胞免疫组学

T细胞免疫应答

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-14959 数据链接链接失效反馈

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scRNA- and TCR-Seq of mouse T cells from WT and TIGIT KO mice at steady state and upon LCMV infection

应用场景：

创建时间：

2025-09-14

单细胞免疫组学

T细胞克隆分析

The goal of this study is to understand the transcriptional features of CD4+ memory T cells induced by CMV seropositivity and explore their TCR repertoire clonality. Overall design: We selected CMV-as

NIAID Data Ecosystem50

ref_LCMV_CD4_mouse_release_v1.rds

单细胞RNA测序

T细胞免疫应答

GP66:I-A b+ spleen T cells were sorted from LCMV infected animals either 7 or 21 days after Clone 13 infection, conditions referred to as Early and Late Chronic. In addition, similar populat

Figshare2021-10-12 更新40

Loss in CD4 T-cell responses to multiple epitopes in influenza due to expression of one additional MHC class II molecule in the host.

T细胞免疫应答

MHC限制性

The epitope sequence was cited in Nayak et al. Viral Immunol. 2010 Apr;23(2):169-80 [PMID:20373997]. Similar results were seen for (B10 x B10.S) F1 mice (H-2bxs). Also, little apparent difference was

ImmuneData30

Targeting CD38 with Daratumumab in refractory Systemic Lupus Erythematosus

单细胞免疫组学

系统性红斑狼疮

Single cell transcriptome and TCR sequencing of FACS-sorted memory T cells in one patient under treatment with the anti CD38-antibody Daratumumab. The patient received Daratumumab at days 0, 7, 14 and

NIAID Data Ecosystem50

Effect of IL-6 on antigen-specific CD8+ T cell activation in vitro

T细胞免疫应答

细胞信号调控

Interleukin 6 (IL-6) is a pleiotropic cytokine with diverse roles in homeostasis, inflammation, and cancer. Here we performed transcriptional profiling of OT-I CD8+ T cells activated in the presence o

NIAID Data Ecosystem40

scRNA- and TCR-Seq of mouse T cells from WT and TIGIT KO mice at steady state and upon LCMV infection

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