Monocle 3 CDS pseudotime objects of FACS-sorted (CD31+/CD45-) endothelial cells

Monocle 3 CDS pseudotime objects of FACS-sorted (CD31+/CD45-) endothelial cells -> part of the manuscript: Single-cell atlas of the human brain vasculature across development, adulthood and diseasehttps://www.nature.com/articles/s41586-024-07493-y ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- -i) Adult control brain (temporal lobe) sorted endothelial cells_cds monocle object.rds: -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from adult/control brains (temporal lobes).-ii) Fetal CNS sorted endothelial cells_cds monocle object.rds: -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from fetal brain (Fetal CNS).- iii) AVM sorted endothelial cells_cds monocle object.rds: -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain arteriovenous malformations (AVM) (a brain vascular malformation).- iv) LGG sorted endothelial cells_cds monocle object.rds: -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from lower-grade gliomas (LGG) (a brain tumor).- v) GBM sorted endothelial cells_cds monocle object.rds: -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from high-grade gliomas (glioblastoma (GBM)) (a brain tumor).- vi) MET sorted endothelial cells_cds monocle object.rds: -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain metastasis (MET) (a brain tumor).- vii) MEN sorted endothelial cells_cds monocle object.rds: -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain meningioma (MEN) (a brain tumor).-viii) Overall merge of tumor sorted endothelial cells_cds monocle object.rds: -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain tumors (lower-grade glioma, high-grade glioma (glioblastoma), brain metastasis, meningiomas). -ix) Overall merge of pathological sorted endothelial cells_cds monocle object.rds: -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain tumors (lower-grade glioma, high-grade glioma (glioblastoma), brain metastasis, meningiomas) and brain vascular malformations (brain arteriovenous malformations).本数据集为经荧光激活细胞分选（Fluorescence-Activated Cell Sorting, FACS）获得的CD31+/CD45-内皮细胞的Monocle 3细胞数据集（CellDataSet, CDS）拟时对象，相关研究论文为《发育、成年与疾病状态下人类脑血管的单细胞图谱》（https://www.nature.com/articles/s41586-024-07493-y）。 i) 成人对照脑（颞叶）分选内皮细胞_cds monocle object.rds：该对象为从成人对照脑颞叶组织中分离得到的、经FACS分选的CD31+/CD45-内皮细胞的Monocle 3 CDS拟时对象。 ii) 胎儿中枢神经系统分选内皮细胞_cds monocle object.rds：该对象为从胎儿脑（胎儿中枢神经系统，Central Nervous System, CNS）中分离得到的、经FACS分选的CD31+/CD45-内皮细胞的Monocle 3 CDS拟时对象。 iii) 脑动静脉畸形分选内皮细胞_cds monocle object.rds：该对象为从脑动静脉畸形（Arteriovenous Malformation, AVM）——一种脑血管畸形——患者脑组织中分离得到的、经FACS分选的CD31+/CD45-内皮细胞的Monocle 3 CDS拟时对象。 iv) 低级别胶质瘤分选内皮细胞_cds monocle object.rds：该对象为从低级别胶质瘤（Lower-grade Gliomas, LGG）——一种脑肿瘤——患者脑组织中分离得到的、经FACS分选的CD31+/CD45-内皮细胞的Monocle 3 CDS拟时对象。 v) 胶质母细胞瘤分选内皮细胞_cds monocle object.rds：该对象为从高级别胶质瘤（胶质母细胞瘤, Glioblastoma, GBM）——一种脑肿瘤——患者脑组织中分离得到的、经FACS分选的CD31+/CD45-内皮细胞的Monocle 3 CDS拟时对象。 vi) 脑转移瘤分选内皮细胞_cds monocle object.rds：该对象为从脑转移瘤（Brain Metastasis, MET）——一种脑肿瘤——患者脑组织中分离得到的、经FACS分选的CD31+/CD45-内皮细胞的Monocle 3 CDS拟时对象。 vii) 脑膜瘤分选内皮细胞_cds monocle object.rds：该对象为从脑膜瘤（Meningioma, MEN）——一种脑肿瘤——患者脑组织中分离得到的、经FACS分选的CD31+/CD45-内皮细胞的Monocle 3 CDS拟时对象。 viii) 肿瘤分选内皮细胞整合数据集_cds monocle object.rds：该对象为整合了低级别胶质瘤、高级别胶质瘤（胶质母细胞瘤）、脑转移瘤、脑膜瘤患者脑组织中分离得到的经FACS分选的CD31+/CD45-内皮细胞的Monocle 3 CDS拟时对象。 ix) 病理状态分选内皮细胞整合数据集_cds monocle object.rds：该对象为整合了脑肿瘤（低级别胶质瘤、高级别胶质瘤（胶质母细胞瘤）、脑转移瘤、脑膜瘤）及脑血管畸形（脑动静脉畸形）患者脑组织中分离得到的经FACS分选的CD31+/CD45-内皮细胞的Monocle 3 CDS拟时对象。