MRI analysis_for Dryad

Excel spreadsheet containing analyzed MRI data. The “MRI ROI comparison” tab contains mean relaxation time constants for each ROI in each animal for each sequence, as well as means for each genotype. The “MRI vs histology” tab contains correlation of tissue section-derived normalized optical density with MRI relaxation time constants for each MRI sequence. The “Outliers” tab contains analysis of each animal for outlying values (see the publication in PLOS ONE for details). Mice 13021, 13224, 13255, N3, N4, and N5 are mice with MPS I; mice 13257, 13258, N1, N2, and N6 are heterozygotes.

本Excel电子表格包含经分析的磁共振成像（MRI，Magnetic Resonance Imaging）数据。其中“MRI ROI 对比”工作表包含每只实验动物在各成像序列下的各感兴趣区（ROI，Region of Interest）的平均弛豫时间常数，以及各基因型的平均弛豫时间常数；“MRI 与组织学对照”工作表包含各成像序列下，组织切片衍生的归一化光密度与磁共振成像弛豫时间常数之间的相关性数据；“异常值”工作表包含每只实验动物的异常值分析（详细信息请参阅发表于PLOS ONE的研究论文）。13021、13224、13255、N3、N4及N5号小鼠为黏多糖贮积症I型（MPS I）模型小鼠；13257、13258、N1、N2及N6号小鼠为杂合子。