Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans

RNA-seq of C.elegans strain N2 (wt) with and without sfa-1 RNAi at adult day 3 and day 15, C. elegans strain DA1116 (eat-2(ad1116)) with and without sfa-1 RNAi at adult day 3, day 15, and day 27, C. elegans strain SS104 (glp-4(bn2)) with and without hrp-2 RNAi at adult day 1, and HeLa cells with and without SF1 siRNA.

本数据集为RNA测序（RNA-seq）样本集，涵盖如下四组实验材料：1. N2野生型（wt）秀丽隐杆线虫（Caenorhabditis elegans）：分别在成虫第3天和第15天，设置施加sfa-1 RNA干扰（RNAi）与未施加干扰的两个亚组；2. DA1116品系（基因型为eat-2(ad1116)）秀丽隐杆线虫：分别在成虫第3天、第15天及第27天，设置施加sfa-1 RNA干扰与未施加干扰的两个亚组；3. SS104品系（基因型为glp-4(bn2)）秀丽隐杆线虫：在成虫第1天，设置施加hrp-2 RNA干扰与未施加干扰的两个亚组；4. HeLa细胞：设置施加SF1小干扰RNA（siRNA）与未施加干扰的两个亚组。