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Copper-Catalyzed Intramolecular N–S Bond Formation by Oxidative Dehydrogenative Cyclization

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Figshare2016-02-19 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Copper_Catalyzed_Intramolecular_N_S_Bond_Formation_by_Oxidative_Dehydrogenative_Cyclization/2394649
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资源简介:
Copper-catalyzed synthesis of benzo­[d]­isothiazol-3­(2H)-ones and N-acyl-benzothiazetidine by intramolecular dehydrogenative cyclization is described. In this reaction, a new nitrogen–sulfur (N–S) bond is formed by N–H/S–H coupling. The present reaction has high functional group tolerance and gives products in gram scale. This method promotes double cyclization, allowing for synthesis of a drug intermediate.
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2016-02-19
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