Peri-surgical inflammatory profile associated with mini-invasive or standard open lumbar interbody fusion ap-proaches

68 healthy subjects affected by single-level discopathy (L3 to S1) were addressed to anterior (ALIF, n= 21), transforaminal (TLIF, n= 24), or lateral (LLIF, n= 23) approaches, based on the preoperative clinical assessment. Venous blood samples were taken 24h before the surgery and 24h and 72h after surgery to assess a wide panel of inflammatory and hematological markers.

68名罹患单节段椎间盘病变（L3至S1）的健康受试者，依据术前临床评估结果，分别接受前路腰椎椎体间融合术（Anterior Lumbar Interbody Fusion, ALIF，n=21）、经椎间孔腰椎椎体间融合术（Transforaminal Lumbar Interbody Fusion, TLIF，n=24）及侧路腰椎椎体间融合术（Lateral Lumbar Interbody Fusion, LLIF，n=23）三种手术入路治疗。研究人员于术前24小时、术后24小时与术后72小时采集静脉血样，以检测多类炎症与血液学标志物。