Physical activity during the early years of life and osteoporosis in adulthood: study among users of the Brazilian National Health System

ABSTRACT The objectives of this study were to analyze the association between osteoporosis and current/early physical activity and also to identify whether early sport participation, osteoporosis, age and sex are somehow connected. The study sample included 963 participants. Osteoporosis was diagnosed through medical records. Physical activity in current and the early years of life, age, sex and economic condition were assessed through questionnaires. Abdominal obesity was identified by waist circumference. Results showed that osteoporosis was associated with female sex and higher age. Participants that were active in adulthood had 47% lower chance of osteoporosis (odds ration [OR] = 0.53[0.30-0.93]). Adults that were active in childhood and adolescence had a lower chance of osteoporosis only in the crude model (OR = 0.38[0.22-0.64]). Women that were inactive in their youth were almost five times more likely to have osteoporosis when compared to men under the same conditions (OR = 4.80[2.46-9.37]). A lack of sports participation in the early years of life seems to be associated with osteoporosis, age and sex.

摘要
本研究旨在分析骨质疏松症与当前及生命早期体力活动之间的关联，并探究早期运动参与、骨质疏松症、年龄与性别之间的内在联系。本研究共纳入963名研究对象。骨质疏松症通过受试者的医疗记录进行确诊。研究通过问卷调查收集了受试者当前及生命早期的体力活动情况、年龄、性别与经济状况，并通过腰围测量识别腹部肥胖。研究结果显示：骨质疏松症与女性性别及高龄存在显著关联；成年时期保持体力活动的受试者，其骨质疏松症患病风险降低47%（优势比[odds ratio, OR]=0.53[0.30-0.93]）；童年及青少年时期参与体力活动的受试者，仅在粗模型分析中表现出更低的患病风险（OR=0.38[0.22-0.64]）；与同等条件的男性相比，青年时期缺乏运动的女性患骨质疏松症的风险几乎为前者的5倍（OR=4.80[2.46-9.37]）。生命早期缺乏运动参与似乎与骨质疏松症、年龄及性别存在关联。