Rhodium(II)-Catalyzed Asymmetric Sulfur(VI) Reduction of Diazo Sulfonylamidines

Diazo sulfonylamidines readily undergo enantioselective
oxygen
transfer from sulfur to carbon atom in the presence of chiral rhodium­(II)
carboxylates resulting in chiral sulfinylamidines. This unusual asymmetric
atom transfer “reduction” occurs rapidly under mild
conditions, and sulfinylamidines are obtained in excellent yield.

重氮磺酰脒（Diazo sulfonylamidines）在手性羧酸铑(II)（chiral rhodium(II) carboxylates）存在下，易于发生硫原子向碳原子的对映选择性氧转移反应，生成手性亚磺酰脒（chiral sulfinylamidines）。该非常规的不对称原子转移“还原”反应可在温和条件下快速进行，且产物亚磺酰脒可获得优异收率。