Long-read transcriptome data (Iso-Seq) of the human and mouse brain

Datasets from "<strong>Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing</strong>", SK.Leung, A.Jeffries. et al. (2021) Deposited files are generated from running Cupcake, SQANTI2 (v7.4) and filter. <br> Note, only the files generated from SQANTI2 filtering are deposited. <br> To re-run SQANTI, use the files in cupcake_collapse folder as input. Please refer to code (https://github.com/SziKayLeung/Whole_Transcriptome_Paper) for more information. Datasets: <br> - AdultCTX: Adult human prefrontal cortex tissue (n = 4) merged dataset<br> - FetalCTX: Fetal human prefrontal cortex tissue (n = 3) merged dataset<br> - FetalHIP: Fetal human hippocampus tissue (n = 2, subset of FetalCTX) merged dataset<br> - FetalSTR: Fetal human striatum tissue (n = 2, subset of FetalCTX) merged dataset<br> - MouseCTX: Mouse entorhinal cortex tissue (n = 12) merged dataset本数据集源自论文《人类与小鼠大脑皮层全长转录组测序揭示广泛的转录本多样性与可变剪接》（Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing），作者为SK.Leung、A.Jeffries等（2021年）。所存储的文件均通过运行Cupcake、SQANTI2（v7.4）及过滤流程生成。<br>注：仅存储经SQANTI2过滤得到的生成文件。<br>若需重新运行SQANTI工具，请以cupcake_collapse文件夹内的文件作为输入。更多相关信息可参考代码仓库：https://github.com/SziKayLeung/Whole_Transcriptome_Paper。本次公开的数据集如下：<br>- AdultCTX：成人前额叶皮层组织（n=4）合并数据集<br>- FetalCTX：胎儿前额叶皮层组织（n=3）合并数据集<br>- FetalHIP：胎儿海马体组织（n=2，为FetalCTX的子集）合并数据集<br>- FetalSTR：胎儿纹状体组织（n=2，为FetalCTX的子集）合并数据集<br>- MouseCTX：小鼠内嗅皮层组织（n=12）合并数据集