Aortic Valve Tissue: Stenosis vs. Sclerosis

We are looking at differential gene/protein expression in tissue from stenotic vs sclerotic human aortic valves in order to identify genetic predispositions for aortic valve disease, as well as novel targets for diagnostic and therapeutic strategies. Two-condition experiment, 3 stenotic vs 3 sclerotic human aortic valve samples

本研究聚焦于狭窄性与硬化性人主动脉瓣组织的差异基因/蛋白质表达分析，旨在明确主动脉瓣疾病的遗传易感性，并挖掘诊断与治疗策略的新型靶点。本实验为双条件对照实验，设置3例狭窄性人主动脉瓣样本与3例硬化性人主动脉瓣样本。