Summary of the number of SNPs with significantly different frequencies between two populations based on the 1000 Genome Project.
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The number in a cell means the number of SNPs with significantly different frequencies (with multiple test corrected -values , see Materials and Methods for details) between the two populations of the row and column. There are 4 populations in the 1000 Genome Project data. ASN includes the CHB, CHS and JPT; AMR includes CLM, MXL (the same as MEX in the HapMap data) and PUR; AFR includes ASW and LWK; and EUR includes CEU, FIN, GBR, IBS and TSI, respectively. Among these populations, the ASW, CEU, CHB, JPT, LWK, MEX, TSI and YRI represent the same populations in Figure 6. Beside these, CHS, CLM, FIN, GBR, IBS, and PUR stand for Han Chinese South; Colombian in Medellin, Colombia; Finnish from Finland; British from England and Scotland; Iberian populations in Spain; and Puerto Rican in Puerto Rico, respectively.
各单元格内的数值代表行与列所对应两个群体间,等位基因频率存在显著差异的单核苷酸多态性(Single Nucleotide Polymorphism, SNP)位点数量(经多重检验校正的P值,详细实验方法参见材料与方法部分)。
本研究使用的千人基因组计划(1000 Genome Project)数据共包含4个超级人群组:亚洲人群(ASN)包含中国北京汉族(CHB)、中国南方汉族(CHS)以及日本人群(JPT);美洲人群(AMR)包含哥伦比亚裔美国人(CLM)、墨西哥裔美国人(MXL,与HapMap数据中的MEX一致)以及波多黎各裔美国人(PUR);非洲人群(AFR)包含非洲裔美国人(ASW)以及肯尼亚卢赫雅族(LWK);欧洲人群(EUR)包含犹他州北欧后裔(CEU)、芬兰本土芬兰人群(FIN)、英格兰与苏格兰裔英国人群(GBR)、西班牙伊比利亚本土人群(IBS)以及托斯卡纳意大利人群(TSI)。
上述群体中,ASW、CEU、CHB、JPT、LWK、MEX、TSI以及约鲁巴人群(YRI)与图6中的对应群体完全一致。
除此以外,CHS、CLM、FIN、GBR、IBS及PUR分别代表中国南方汉族、哥伦比亚麦德林市哥伦比亚裔人群、芬兰本土芬兰人群、英格兰与苏格兰裔英国人群、西班牙伊比利亚本土人群以及波多黎各波多黎各裔人群。
创建时间:
2015-12-02



