Cognitive performance dependent on familial longevity (offspring versus partner status*).
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*Offspring = 0, partner = 1.†Values are expressed as mean (standard error).‡n = 223 for offspring and n = 223 for partners. Abbreviations: β, estimate; CI, confidence interval; 15-PLT, 15-Picture Learning Test; DSST, Digit Symbol Substitution Test. Model 1: adjusted for age, gender and years of education. Model 2: as model 1+ diabetes mellitus, cardiovascular diseases (myocardial infarction, stroke and hypertension), alcohol use, smoking, high-sensitivity C-reactive protein, interleukin-6 and apolipoprotein E genotype. Robust standard errors were used to account for familial relationships among the offspring.
* 子代(Offspring)赋值为0,伴侣(partner)赋值为1。 † 所有数值以均值(标准误)表示。 ‡ 子代样本量为223,伴侣样本量亦为223。 缩写说明:β为参数估计值(β, estimate);CI为置信区间(confidence interval);15-PLT为15图片学习测验(15-Picture Learning Test);DSST为数字符号替换测验(Digit Symbol Substitution Test)。 模型1:校正年龄、性别与受教育年限。 模型2:以模型1的校正变量为基础,额外纳入糖尿病、心血管疾病(含心肌梗死、脑卒中与高血压)、饮酒情况、吸烟状态、高敏C反应蛋白、白细胞介素-6以及载脂蛋白E基因型进行校正。 本研究采用稳健标准误以校正子代群体间的家族亲缘相关性。




