Basis for selective drug evasion of an aminoglycoside-resistance ribosomal RNA modification

Structural coordinates, cryo-EM maps, and PDB validation reports for three E. coli 70S ribosome-aminoglycoside complex structures. The complexes are:
1. G418 bound to 70S with 16S rRNA m1A1408 modified.
2. Arbekacin bound to 70S with 16S rRNA unmodified.
3. Arbekacin bound to 70S with 16S rRNA modified m1A1408.

本数据集包含3种大肠杆菌（E. coli）70S核糖体-氨基糖苷类复合物结构的结构坐标、冷冻电镜（cryo-EM）图谱以及PDB验证报告。所涉及的复合物如下：
1. 结合G418、带有16S rRNA m1A1408修饰的70S核糖体复合物；
2. 结合阿贝卡星（Arbekacin）、16S rRNA未修饰的70S核糖体复合物；
3. 结合阿贝卡星（Arbekacin）、带有16S rRNA m1A1408修饰的70S核糖体复合物。