20210422_PhysicalRahab_Cognition_last

This is the processed data for the manuscript “Avenali M, Picascia M, Tassorelli C, Sinforiani E, Bernini S. Evaluation of the efficacy of physical therapy on cognitive decline at 6-month follow-up in Parkinson disease patients with mild cognitive impairment: a randomized controlled trial. Aging Clin Exp Res. 2021 May 12. Epub ahead of print”. This dataset includes demographics, clinical and neuropsychological variables of the Parkinson Disease patients with mild cognitive impairment evaluated in the study, in order to asses the efficacy of physical therapy on cognitive decline over a 6 months follow-up. Cognitive and motor assessments were performed at three time points: T0, baseline; T1, 4 weeks after baseline and T2, 6 months after baseline. To assess cognitive profile, we used the following selection of tests to predominantly investigate various features of executive functions: Mini-Mental State Examination (MMSE); Montreal Cognitive Assessment (MoCA); spatial Corsi’s block-tapping test (CB); Raven’s Matrices 1947 (RM47) ; Frontal Assessment Battery (FAB); phonological fluency (FAS); Attentive Matrices, Trail Making Test A and B (TMT-A; TMT-B). Motor performances were assessed by means of MDS-Unified Parkinson’s Disease Rating Scale, part III (UPDRS-III), Tinetti balance and gait score and Hauser Index. Data highlights that physical therapy has a positive effect on cognitive functions which extends beyond the duration of the treatment itself.

本数据集对应论文"Avenali M, Picascia M, Tassorelli C, Sinforiani E, Bernini S. 轻度认知障碍帕金森病患者物理疗法对6个月随访期认知衰退的疗效评估：一项随机对照试验. Aging Clin Exp Res. 2021年5月12日，提前在线刊印"的经处理后数据。本数据集收录本研究中评估的轻度认知障碍帕金森病患者的人口学资料、临床指标与神经心理学变量，以评估物理疗法在6个月随访周期内对认知衰退的改善效果。认知与运动功能评估分别于三个时间点开展：T0（基线）、T1（基线后4周）及T2（基线后6个月）。为评估认知特征，本研究选用以下测试组合以重点考察执行功能的多个维度：简易精神状态检查表（Mini-Mental State Examination, MMSE）、蒙特利尔认知评估量表（Montreal Cognitive Assessment, MoCA）、空间科西积木点击测试（spatial Corsi’s block-tapping test, CB）、1947版瑞文推理测验（Raven’s Matrices 1947, RM47）、额叶评估量表（Frontal Assessment Battery, FAB）、语音流畅性测验（phonological fluency, FAS）、注意力矩阵测验、连线测验A与B（Trail Making Test A and B, TMT-A; TMT-B）。运动功能表现则通过运动障碍协会统一帕金森病评定量表第三部分（MDS-Unified Parkinson’s Disease Rating Scale, Part III, UPDRS-III）、Tinetti平衡与步态评分以及Hauser指数进行评估。数据结果显示，物理疗法对认知功能具有积极影响，且该效果可延续至治疗结束之后。