Frequency distribution of cytokine and associated transcription factor single nucleotide polymorphisms in Zimbabweans: impact on schistosome infection and cytokine levels

This dataset contains demographic, parasitological, immunological, and single nucleotide polymorphism (SNP) data from 850 Zimbabwean individuals participating in a longitudinal study of urogenital schistosomiasis (S. haematobium) infection. Individuals from an S. haematobium-endemic region were genotyped for 35 SNPs across genes encoding cytokines and associated transcription factors, and the role of these SNPs in modulating susceptibility to S. haematobium infection and cytokine production was analysed.

本数据集涵盖850名津巴布韦受试者的人口统计学、寄生虫学、免疫学及单核苷酸多态性（single nucleotide polymorphism, SNP）数据，上述受试者参与了一项针对泌尿生殖道血吸虫病（埃及血吸虫，S. haematobium）感染的纵向研究。研究人员对来自埃及血吸虫流行区域的受试者进行基因分型，检测了其细胞因子及相关转录因子编码基因上的35个SNP位点，并分析了这些SNP在调节埃及血吸虫感染易感性与细胞因子产生过程中所发挥的作用。