Study on the mechanism of Qianyang Yuyin Granule regulating Sestrin2/Nrf2/NOX4 pathway to inhibit cell pyroptosis and improve hypertensive kidney damage

The central hypothesis of this study is that Qianyang Yuyin Granule (QYYG) ameliorates hypertensive kidney injury by modulating the Sestrin2/Nrf2/NOX4 signaling pathway, leading to a reduction in oxidative stress and the inhibition of cellular pyroptosis.
This dataset constitutes the primary data of the present experimental study, encompassing original Western blot (WB) autoradiograph images, histopathological staining tissue sections, and semi-quantitative statistical data from immunohistochemistry (IHC).

本研究的核心假说为，千阳愈阴颗粒（Qianyang Yuyin Granule）可通过调控Sestrin2/Nrf2/NOX4信号通路改善高血压肾损伤，进而减轻氧化应激并抑制细胞焦亡。
本数据集为本项实验研究的核心原始数据，涵盖原始蛋白质免疫印迹（Western Blot, WB）放射自显影图像、组织病理学染色切片，以及免疫组织化学（Immunohistochemistry, IHC）的半定量统计数据。