Profiling of <i>Rosa hybrida</i> cv. Mileva essential oil, evaluation of its bioactivity <i>in vitro</i>, chemometric analysis and comparison to other non-commercial roses

Rose essential oil is one of the most valuable and pivotal raw materials in the perfume industry. However, the limited yield of essential oil in rose flowers increased the interest of both breeders and scientists to create and discover species that have potential for multifaceted applications aiming to increase the economic viability of rose cultivation. Consequently, garden roses (<i>Rosa hybrida</i>) through ongoing development emerge as possibly profitable for cultivation and processing. This opens possibilities for numerous applications in both food and pharmaceutical industries. The main objective of this study was to identify the essential oil composition of <i>R. hybrida</i> cv. Mileva and compare it against essential oil chemical compositions of 32 accessions of other non-commercial (wild and hybrid) roses available literature. The dominant compound detected in <i>R. hybrida</i> cv. Mileva essential oil was geranyl acetate (47.9%), followed by nonadecane and heneicosane. It was shown that the essential oil possesses moderate antimicrobial activity, good antioxidant potential and strong anti-inflammatory activity.玫瑰精油是香水工业中最具价值与核心地位的原料之一。然而玫瑰花精油产量有限，这使得育种者与科研人员愈发渴望培育、发掘具备多方面应用潜力的品种，以提升玫瑰种植的经济可行性。因此，经过持续改良的园艺玫瑰（<i>Rosa hybrida</i>）逐渐展现出具备种植与加工的可观经济效益，这为其在食品与制药工业中的多元应用开辟了空间。本研究的核心目标为鉴定杂种玫瑰（<i>R. hybrida</i>）品种‘Mileva’的精油成分，并将其与现有文献中记载的32份非商用（野生及杂交）玫瑰种质的精油化学组成进行对比。在‘Mileva’品种的玫瑰精油中，检测到的优势成分为乙酸香叶酯（geranyl acetate，47.9%），其次为十九烷（nonadecane）与二十一烷（heneicosane）。研究表明，该精油具备中等强度的抗菌活性、良好的抗氧化潜能以及显著的抗炎活性。