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CpG methylation beta values and sample age for the advanced forensic biology lesson

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Zenodo2020-09-28 更新2026-05-25 收录
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This dataset should be used for the practical of the "Advanced Forensic Biology" lesson. It has been slightly modified from the initial source (see below). It consists of two parts: <strong>1) CpG methylation beta values</strong>: tabulated separated methylation beta values in a file called cpg_methylation_beta_values.tsv. <strong>2) Samples to chronological age </strong>: the relationship between sample identifiers and their chronological age in a tabulated separated file called cpg_methylation_sample_age.tsv. <strong>3) CpG identifier to gene symbol and annotation:</strong> a tabulated separated file containing the relationship between CpG island identifier, the corresponding gene and its functional annotation. cpg_methylation_cpg_to_annotation.tsv <br> <strong>Dataset provenance:</strong> Bocklandt S, Lin W, Sehl ME, Sánchez FJ, Sinsheimer JS, Horvath S, Vilain E. Epigenetic predictor of age. PLoS One. 2011;6(6):e14821. doi: 10.1371/journal.pone.0014821. Epub 2011 Jun 22. PMID: 21731603; PMCID: PMC3120753. GEO link: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28746

本数据集用于《高级法医生物学》课程的实践教学,其源自初始数据源并经过小幅修改(详见下文)。数据集包含三部分内容: 1. **CpG甲基化β值(CpG methylation beta values)**:存储于文件`cpg_methylation_beta_values.tsv`中,为制表符分隔的甲基化β值表格。 2. **样本与实足年龄对应关系**:存储于文件`cpg_methylation_sample_age.tsv`中,为制表符分隔的样本标识符与其实足年龄的对应关系表格。 3. **CpG标识符-基因符号及功能注释映射**:存储于文件`cpg_methylation_cpg_to_annotation.tsv`中,为包含CpG岛标识符、对应基因及其功能注释的制表符分隔表格。 **数据集溯源**:Bocklandt S、Lin W、Sehl ME、Sánchez FJ、Sinsheimer JS、Horvath S、Vilain E的研究《Epigenetic predictor of age》发表于《PLoS One》,2011年;6(6):e14821。DOI: 10.1371/journal.pone.0014821,2011年6月22日在线发表,PMID: 21731603;PMCID: PMC3120753。GEO数据库链接:https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE28746

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Zenodo
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2020-09-28
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