Table_1_Prevalence of depressive symptoms and correlates among individuals who self-reported SARS-CoV-2 infection after optimizing the COVID-19 response in China.DOCX

BackgroundThe burden of depression symptoms has increased among individuals infected with SARS-CoV-2 during COVID-19 pandemic. However, the prevalence and associated factors of depressive symptoms among individuals infected with SARS-CoV-2 remain uncertain after optimizing the COVID-19 response in China.
MethodsAn online cross-sectional survey was conducted among the public from January 6 to 30, 2023, using a convenience sampling method. Sociodemographic and COVID-19 pandemic-related factors were collected. The depression symptoms were assessed using the Patient Health Questionnaire-9 (PHQ-9). Logistic regression analysis was performed to explore the associated factors with depressive symptoms.
ResultsA total of 2,726 participants completed the survey. The prevalence of depression symptoms was 35.3%. About 58% of the participants reported experiencing insufficient drug supply. More than 40% of participants reported that they had missed healthcare appointments or delayed treatment. One-third of participants responded experiencing a shortage of healthcare staff and a long waiting time during medical treatment. Logistic regression analysis revealed several factors that were associated with depression symptoms, including sleep difficulties (OR, 2.84; 95% CI, 2.34–3.44), chronic diseases (OR, 2.15; 95% CI, 1.64–2.82), inpatient treatment for COVID-19 (OR, 3.24; 95% CI, 2.19–4.77), with COVID-19 symptoms more than 13 days (OR, 1.30, 95% CI 1.04–1.63), re-infection with SARS-CoV-2 (OR, 1.52; 95% CI, 1.07–2.15), and the increased in demand for healthcare services (OR, 1.32; 95% CI, 1.08–1.61).
ConclusionThis study reveals a moderate prevalence of depression symptoms among individuals infected with SARS-CoV-2. The findings underscore the importance of continued focus on depressive symptoms among vulnerable individuals, including those with sleeping difficulties, chronic diseases, and inpatient treatment for COVID-19. It is necessary to provide mental health services and psychological interventions for these vulnerable groups during the COVID-19 epidemic.

背景：新冠疫情（COVID-19 pandemic）期间，感染严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）的人群中抑郁症状负担有所上升。然而，在中国优化新冠疫情防控措施后，感染新冠病毒的人群中抑郁症状的流行率及其相关影响因素仍不明确。
方法：本研究于2023年1月6日至30日采用便利抽样法，面向公众开展线上横断面调查。收集研究对象的社会人口学特征及新冠疫情相关因素信息，采用患者健康问卷9项版（Patient Health Questionnaire-9, PHQ-9）评估其抑郁症状，并通过Logistic回归分析探究抑郁症状的相关影响因素。
结果：本研究共纳入2726名完成问卷的参与者。抑郁症状的流行率为35.3%。约58%的参与者表示存在药物供给不足的情况；超40%的参与者称曾错过医疗预约或延误治疗；三分之一的参与者反馈就医时存在医护人员短缺及等候时间过长的问题。Logistic回归分析显示，多项因素与抑郁症状显著相关：睡眠障碍（比值比OR=2.84，95%置信区间CI：2.34~3.44）、慢性疾病（OR=2.15，95%CI：1.64~2.82）、因新冠住院治疗（OR=3.24，95%CI：2.19~4.77）、新冠症状持续时长超过13天（OR=1.30，95%CI：1.04~1.63）、新冠病毒二次感染（OR=1.52，95%CI：1.07~2.15）以及医疗服务需求增加（OR=1.32，95%CI：1.08~1.61）。
结论：本研究显示，感染新冠病毒的人群中抑郁症状呈现中等程度的流行率。研究结果强调，需持续关注存在睡眠障碍、慢性疾病及因新冠住院治疗等脆弱群体的抑郁症状情况；在新冠疫情期间，应为上述脆弱群体提供心理健康服务及心理干预措施。