Biomodal role of H3.3 in safe-guarding and establishing cell identities during reprogramming [ChIP-Seq]

Identification of the genome-wide enrichment of H3.3, H3K4me3 and H3K36me3 during cellular reprogramming using ChIP-Seq Overall design: ChIP-Seq of H3.3, H3K4me3 and H3K36me3 at seveal time-points during cellular reprogramming or transdifferentiation

利用ChIP-Seq（Chromatin Immunoprecipitation Sequencing，染色质免疫共沉淀测序）技术，鉴定细胞重编程过程中H3.3、H3K4me3与H3K36me3的全基因组富集特征。实验整体设计：在细胞重编程或转分化的多个时间点，对H3.3、H3K4me3及H3K36me3开展ChIP-Seq测序。