Evaluation of ionic dissociation of calcium hydroxide associated with Aloe vera as vehicle

Abstract Introduction Calcium hydroxide is considered an intracanal medication gold standard, and different substances can be employed as a vehicle to improve its properties. Aloe vera is a herbal remedy popularly known as babosa and is notable for its immunoregulatory, antimicrobial, healing and cellular biocompatibility. Objective To evaluate the ionic dissociation of calcium hydroxide, with the Aloe vera as vehicle. Material and method The extract of Aloe vera was obtained directly from the leaf, submitted to filtration and stored in a sterile falcon tube. Two groups of intracanal medication were prepared; the control group, with calcium hydroxide and saline; and the experimental group, with calcium hydroxide and Aloe vera as vehicle. Result There was no statistically significant difference between the means of calcium release from the groups (p = 0.944). When comparing the paired values, considering the different evaluations over time, a statistically significant difference (p = 0.015) was identified for the experimental group, so that mean values of calcium released were higher up to the 21st day of the study. Conclusion Calcium hydroxide, when associated with Aloe vera, presented higher ionic dissociation than when used with distilled water. This result, combined with the inherent properties of this herbal remedy, suggests that the paste of calcium hydroxide and Aloe vera can be a viable and promising alternative as intracanal medication and improve apical and periapical repair.

【摘要 引言】氢氧化钙被视为根管内用药的金标准，可通过不同载体改善其性能。芦荟（Aloe vera）是一种俗称“巴巴多斯芦荟”的草药，因其具备免疫调节、抗菌、促愈合及细胞生物相容性等特性而广受认可。
目的 本研究旨在评估以芦荟为载体时氢氧化钙的离子解离情况。
材料与方法 芦荟提取物直接取自叶片，经过滤处理后储存于无菌Falcon管中。制备两组根管内用药：对照组为氢氧化钙联合生理盐水；实验组为以芦荟作为载体的氢氧化钙制剂。
结果 两组间钙释放量的均值无统计学显著性差异（p=0.944）。对随时间变化的配对检测值进行比较时，实验组呈现统计学显著性差异（p=0.015），其钙释放均值在研究至第21天时达到峰值。
结论 与以蒸馏水作为载体的情况相比，氢氧化钙与芦荟联合使用时的离子解离程度更高。结合该草药本身的固有特性，这一结果表明氢氧化钙-芦荟糊剂可作为一种可行且极具前景的根管内用药替代方案，有助于优化根尖及根尖周组织的修复效果。