Additional file 10: of Relationships between putative G-quadruplex-forming sequences, RecQ helicases, and transcription

R code for extracting histone modification track signal near TSS for epigenetic modeling of gene expression method. Program written in R that calculates histone modification track signal in 100 bp bins spanning 1 kbp upstream and downstream of the TSS. Takes multiple .bigwig files of histone modification epigenomic tracks and the output of Additional file 9 as input. (R 5 kb)

本R代码用于提取转录起始位点（Transcription Start Site, TSS）附近的组蛋白修饰轨道信号，适配基因表达的表观遗传建模方法。该程序采用R语言编写，可在转录起始位点上下游各1千碱基对（kilobase pair, kbp）的区域内，以100碱基对（base pair, bp）为分箱单元计算组蛋白修饰轨道信号。程序接收多个组蛋白修饰表观基因组轨道的.bigwig文件以及附加文件9的输出结果作为输入。（R语言实现，文件大小约5 KB）