Comparison of single-cell whole-genome amplification strategies

We compared the performance of six different single-cell whole-genome amplification methods after amplifying and low-pass sequencing the complete genome of 230 healthy and tumoral human cells.本研究对230例健康及肿瘤源性人类细胞的完整基因组进行扩增并开展低覆盖度测序（low-pass sequencing），以此对比六种不同单细胞全基因组扩增（single-cell whole-genome amplification）方法的性能。