Samples for CNIC-Proteomics Nextflow pipelines: nf-SearchEngine

We present several input sample files for the execution of various Nextflow pipelines developed by the Cardiovascular Proteomics Lab/Proteomics Unit at the National Centre for Cardiovascular Research (CNIC, https://www.cnic.es). The nf-SearchEngine executes the MSFragger search engine for peptide identification (https://github.com/CNIC-Proteomics/nf-SearchEngine). The available sample files are as follows: heteroplasmic_heart.zip: Heart tissues. Input files for nf-SearchEngine, derived from the study by Bagwan N, Bonzon-Kulichenko E, Calvo E, et al. (*), including Thermo raw files in mzML format and other data. heteroplasmic_liver.zip: Livertissues. Input files for nf-SearchEngine, derived from the same study (*), including Thermo raw files in mzML format and other data. heteroplasmic_muscle.zip: Muscle tissues. Input files for nf-SearchEngine, derived from the same study (*), including Thermo raw files in mzML formatand other data. (*) Bagwan N, Bonzon-Kulichenko E, Calvo E, et al. Comprehensive Quantification of the Modified Proteome Reveals Oxidative Heart Damage in Mitochondrial Heteroplasmy. Cell Reports. 2018;23(12):3685-3697.e4. doi:10.1016/j.celrep.2018.05.080本数据集提供若干输入样本文件，用于运行西班牙国家心血管研究中心（CNIC，https://www.cnic.es）心血管蛋白质组学实验室/蛋白质组学单元开发的多款Nextflow流程。 nf-SearchEngine流程用于调用MSFragger搜索引擎实现肽段鉴定，其开源仓库地址为https://github.com/CNIC-Proteomics/nf-SearchEngine。 可用样本文件如下： heteroplasmic_heart.zip：心脏组织样本。该数据集为nf-SearchEngine的输入文件，源自Bagwan N、Bonzon-Kulichenko E、Calvo E等人的研究(*)，包含格式为mzML的赛默飞世尔（Thermo）原始文件及其他相关数据。 heteroplasmic_liver.zip：肝脏组织样本。该数据集为nf-SearchEngine的输入文件，源自上述同一研究(*)，包含格式为mzML的赛默飞世尔（Thermo）原始文件及其他相关数据。 heteroplasmic_muscle.zip：肌肉组织样本。该数据集为nf-SearchEngine的输入文件，源自上述同一研究(*)，包含格式为mzML的赛默飞世尔（Thermo）原始文件及其他相关数据。 (*) Bagwan N, Bonzon-Kulichenko E, Calvo E 等. 修饰蛋白质组的定量分析揭示线粒体异质性相关心脏氧化损伤[J]. 《细胞报告》（Cell Reports）, 2018, 23(12): 3685-3697.e4. DOI: 10.1016/j.celrep.2018.05.080