Whole genome sequencing demonstrates limited transmission within identified Mycobacterium tuberculosis clusters in New South Wales, Australia. WGS analysis of MIRU-24 clusters in NSW, Australia

We reviewed MIRU-24 profiles of all culture-confirmed cases diagnosed from 2009-2013 in New South Wales, Australia. Whole genome sequencing was performed on the largest MIRU-24 clusters identified with detailed phylogenetic analysis to assess the relatedness of strains within each cluster.

本研究回顾了澳大利亚新南威尔士州2009年至2013年所有经培养确诊的病例的24位点分枝杆菌间隔重复序列分型（MIRU-24）谱。针对所鉴定出的最大MIRU-24聚类簇，我们开展了全基因组测序，并进行详细的系统发育分析，以评估各簇内菌株的亲缘关系。