Raw sgRNA counts for A549 p53wt.

NIAID Data Ecosystem2026-03-12 收录

CRISPRi筛选

癌细胞系

数据链接：

https://figshare.com/articles/dataset/Raw_sgRNA_counts_for_A549_p53wt_/14354369 数据链接链接失效反馈

官方服务：

资源简介：

sgRNA, single gRNA; wt, wild-type. (XLSX)

sgRNA即单gRNA（single gRNA）；wt即野生型（wild-type）。（XLSX）

创建时间：

2021-03-31

Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [TargetedCRISPRscreen]

白血病发病机制

CRISPRi筛选

Investigating Bcor target genes in BcorΔE9-10KrasG12D leukaemia with a custom CRISPR dropout screen BcorΔE9-10KrasG12D cell line was transduced with a custom CRISPR library and a dropout screen was pe

NIAID Data Ecosystem30

Essential gene profiles for human pluripotent stem cells identify uncharacterized genes and substrate dependencies. Mair et al.

干细胞鉴定

CRISPRi筛选

Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding pluripotency and lineage differentiation mechanisms,

NIAID Data Ecosystem20

Genes of CRISPR-Cas9 negative screening.

CRISPRi筛选

肿瘤免疫逃逸

We compared changes in sgRNA abundance between T24 cells challenged and unchallenged by CD8+ T cells, and then performed negative screening (p < 0.01, log2Fold change < −1.0, and good sgRNAs ≥ 5). (X

NIAID Data Ecosystem10

Genome-scale CRISPRi Perturb-seq on both unstimulated and stimulated Jurkat cells reveals regulators of human T-cell signaling

T细胞信号传导调控

CRISPRi筛选

The goal of the experiment is to identify genes involved in T-cell receptor (TCR) signaling and T-cell activation in human T cells. The Jurkat E6 cell line, engineered to express dCas9-KRAB and transd

NIAID Data Ecosystem20

Gene expression of osteosarcoma cell (U2OS, MG63) lines relative to normal human osteoblasts (HOB)

肉瘤基因表达

癌细胞系

Gene expression of osteosarcoma cell (U2OS, MG63) lines relative to normal human osteoblasts (HOB)

ChEBI2009-05-01 更新10