Acute toxicity analysis – Escalating doses using a single mice (starting at 20 mg/kg up to 400 mg/kg DB1965 – ip – using 0.1 mL final volume per mice): Swiss male and female mice (20–23 g).

NOAEL (No observed adverse effect level).All assays were run at least two times.未观察到有害作用水平（No Observed Adverse Effect Level，NOAEL）。所有检测实验均至少重复运行两次。