Homo sapiens Raw sequence reads. Homo sapiens

we designed a novel editing strategy, named TD-PE (tandem duplication via prime editing), to precisely create tandem duplication in the mammalian genome, with the length of the duplication ranging from tens to thousands of base pairs.

我们设计了一种名为TD-PE（引物编辑介导的串联重复，tandem duplication via prime editing）的新型基因组编辑策略，可在哺乳动物基因组中精准构建串联重复序列，其重复片段的长度范围为数十至数千碱基对。