Usher syndrome study.sav

The aim of this study was to determine if psychosocial wellbeing predicts the health-related quality of life (HRQOL) of people with Usher syndrome. Ninety UK-resident adults with Usher syndrome were recruited through deafblind-related charities, support groups and social groups. All participants took part in a survey that measured their physical and mental HRQOL, depressive symptoms, loneliness and social support. Measured confounders included age, sex and health-related characteristics. Hierarchical multiple linear regression analyses examined the association of each psychosocial wellbeing indicator with both physical and mental HRQOL while controlling for confounders in a stepwise manner.

本研究旨在明确心理社会福祉是否可预测尤塞恩综合征（Usher syndrome）患者的健康相关生活质量（health-related quality of life，HRQOL）。研究通过聋盲相关慈善机构、支持团体及社交团体，招募了90名居住于英国的尤塞恩综合征成人受试者。所有受试者均参与了一项调查，该调查评估了其生理与心理健康相关生活质量、抑郁症状、孤独感及社会支持水平。本次研究测量的混杂因素包括年龄、性别及健康相关特征。采用分层多元线性回归分析，通过逐步控制混杂因素，检验各心理社会福祉指标与生理、心理健康相关生活质量之间的关联。