ACTIVATION AND TARGETABILITY OF TYMP-IL-6-TF SIGNALING IN THE SKIN MICROENVIRONMENT IN UREMIC CALCIPHYLAXIS

This repository contains merged RNA-seq raw count data and count data after normalization described in the papaer with Rstudio and Python3 code to re-create the Olink protein abundancy results, differential gene exression results, ligand-receptor analysis results (in DEG_LR.zip) and ROI-ROI communication probability results (in spOTsc_remake.zip) and make plots shown in the paper.

本仓库包含本文所描述的整合RNA测序（RNA-seq）原始计数数据与标准化计数数据，同时附带RStudio与Python3代码，可复现论文中的Olink蛋白质丰度分析结果、差异基因表达分析结果、配体-受体分析结果（存于DEG_LR.zip压缩包中）以及感兴趣区域（Region of Interest，ROI）间通信概率分析结果（存于spOTsc_remake.zip压缩包中），并可生成论文中展示的各类可视化图表。