Whole Exome Sequencing (WES) data from a dog diagnosed with unroofed coronary sinus (UCS)

This dataset contains raw and processed whole exome sequencing (WES) data from a Pomeranian dog diagnosed with a rare congenital heart defect, unroofed coronary sinus (UCS). The data were analyzed to identify potential missense SNVs that may contribute to the pathogenesis of UCS. This resource supports the findings presented in the article titled “A rare case of asymptomatic unroofed coronary sinus in a dog: diagnostic imaging and genetic findings,” published in <i>Frontiers in Veterinary Science</i> (2025).

本数据集包含一只确诊为罕见先天性心脏缺陷——冠状窦无顶综合征（unroofed coronary sinus, UCS）的博美犬的原始与经处理的全外显子组测序（whole exome sequencing, WES）数据。本研究通过对该数据集进行分析，旨在识别可能参与UCS发病机制的潜在错义单核苷酸变异（single nucleotide variant, SNV）。本资源可为发表于2025年《兽医科学前沿》（Frontiers in Veterinary Science）的题为《犬无症状冠状窦无顶综合征罕见病例：诊断影像学与遗传学发现》的文章所呈现的研究结果提供支撑。