HSF1 activation

This event has been computationally inferred from an event that has been demonstrated in another species.<p>The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.<p><a href='/electronic_inference_compara.html' target = 'NEW'>More details and caveats of the event inference in Reactome.</a> For details on PANTHER see also: <a href='http://www.pantherdb.org/about.jsp' target='NEW'>http://www.pantherdb.org/about.jsp</a>

本事件系通过计算推理自另一物种已验证的事件得出。推理过程基于 PANTHER 的同源性映射。简而言之，对于所有涉及的物理实体（包括输入、输出和催化剂）均存在映射同源或旁系同源的反应（对于复合物而言，至少75%的组成部分必须进行映射），将推断至另一物种。此外，对于这些事件，还推断出高级别事件，以便于更便捷的导航。<p>关于 Reactome 事件推理的更多细节及注意事项，请参阅：<a href='/electronic_inference_compara.html' target = 'NEW'>事件推理的详细信息及注意事项</a>。有关 PANTHER 的详细信息，请参阅：<a href='http://www.pantherdb.org/about.jsp' target='NEW'>PANTHER 简介</a>。