Supplemental Table 1 TASK-1 Echo

<b>Supplemental Table 1. TASK-1 Serial Echocardiography after Pressure Overload (TAC) </b> Wild Type and TASK-1 KO mice after Transverse Aortic Constriction (TAC) underwent serial echocardiography measurements of Left Ventricular End Diastolic Dimension (LVEDD), End Systolic Dimension (LVESD), Septal Wall Thickness (SWT), Posterior Wall Thickness (PWT), Heart Rate (HR), LV mass, Relative Wall Thickness (RWT = PWT x 2/ LVEDD), Fraction Shortening (FS= (LVEDD-LVESD)/LVEDD X 100), mean rate corrected velocity of circumferential shortening (mVcFc= Fractional Shortening/ (Aortic Ejection Time/√60/Heart Rate)). Statistical comparison between Wild Type and TASK-1 KO were made using a non-paired two tailed t-test. *p&lt;0.05 vs Wild Type

<b>补充表1. 压力超负荷（横向主动脉缩窄，Transverse Aortic Constriction，TAC）造模后TASK-1基因敲除小鼠的系列超声心动图检测</b>
野生型（Wild Type）与TASK-1基因敲除（TASK-1 KO）小鼠经横向主动脉缩窄术后构建的压力超负荷模型，接受了系列超声心动图指标检测，所测指标包括：左心室舒张末期内径（Left Ventricular End Diastolic Dimension，LVEDD）、左心室收缩末期内径（Left Ventricular End Systolic Dimension，LVESD）、室间隔厚度（Septal Wall Thickness，SWT）、左心室后壁厚度（Posterior Wall Thickness，PWT）、心率（Heart Rate，HR）、左心室质量、相对室壁厚度（Relative Wall Thickness，RWT = PWT×2 / LVEDD）、短轴缩短率（Fractional Shortening，FS=(LVEDD-LVESD)/LVEDD×100）以及平均心率校正的圆周纤维缩短速率（mean rate corrected velocity of circumferential shortening，mVcFc=FS/(主动脉射血时间/√(60/心率))）。
野生型组与TASK-1基因敲除组的统计学比较采用独立样本双侧t检验，*p<0.05表示与野生型组相比差异具有统计学意义。