Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation (Mouse_4M-Prostate_RNA-Seq)

Analysis of transcriptome of prostate tissue from 4-month-old Nkx3.1 +/+ and Nkx3.1 -/- mice. Overall design: Total RNA obtained from prostate tissues from 4-month-old Nkx3.1 +/+ and Nkx3.1 -/- mice. Prostate tissues were harvested and processed for RNA isolation and transcriptome analysis using the MagMAX RNA isolation kit (Ambion).

本研究针对4月龄Nkx3.1野生型（Nkx3.1 +/+）与Nkx3.1纯合敲除型（Nkx3.1 -/-）小鼠的前列腺组织开展转录组分析。实验设计概述：实验所用总RNA提取自上述4月龄两种基因型小鼠的前列腺组织；收集前列腺组织后，采用MagMAX RNA提取试剂盒（Ambion）完成RNA分离，并开展转录组分析。