Screening for Colorectal Cancer in Recipients of Kidney Transplants

Interventions: 1. Faecal occult blood testing (FOBT). Participants will perform FOBT following enrolment. This involves using a patient kit to sample their own stools for the presence of blood, mailing their testing kit in to a central lab once it is completed. Testing will be conducted once but may involve sampling several stools.
2. Colonoscopy. All participants will also undergo colonoscopy following the completion of FOBT, regardless of the result. This will be performed within a target of 3 months post enrolment.
Primary outcome(s): Sensitivity and specificity of faecal occult blood testing for colorectal cancer and colorectal neoplasia, using colonscopy as the gold standard procedure.[One-off screening with both FOBT and colonoscopy, with a completion target of 3 months post enrolment.]
Study Design: Purpose: Screening;Duration: Cross-sectional;Selection: Defined population;Timing: Prospective

干预措施：
1. 粪便隐血试验（Faecal occult blood testing, FOBT）：受试者入组后需完成该检测。具体操作为使用专用采样套件自行采集粪便样本以检测潜血，完成采样后将检测套件邮寄至中央实验室。该检测仅需开展1次，但可多次采集粪便样本。
2. 结肠镜检查（Colonoscopy）：所有受试者无论粪便隐血试验结果如何，均需在粪便隐血试验完成后接受结肠镜检查，检查需在受试者入组后3个月的目标时限内完成。
主要结局指标：以结肠镜检查为金标准操作（gold standard procedure），评估粪便隐血试验对结直肠癌（colorectal cancer）及结直肠肿瘤（colorectal neoplasia）的灵敏度与特异度。[本研究为粪便隐血试验与结肠镜的一次性联合筛查，完成时限为入组后3个月内。]
研究设计：研究目的：筛查；研究类型：横断面研究；研究对象选取：明确划定的人群；研究时序：前瞻性研究