Input structures and accessory data.

This table collects structural parameters for the complexes used in this work, along with chosen parameters like anchor placement. The PDB column identifies the structure. The chains column identifies which complex within the PDB file was used (several have many complexes in the asymmetric unit). *: 2obg was not crystallized as a heterodimer; it was expressed as a fusion protein and crystallized as an infinitely domain-swapped polymer.[24] The resolution column contains the reported crystal structure resolution; all are reasonable. The dimer type column identifies the type of dimer. **: 1dle represents a crystal dimer rather than a biological one, making it a good test of weak interactions. The SASA column notes the area buried by the interface. The anchor and chain columns together identify the residue used as an anchor. The loop column identifies which residues (on the same chain as the anchor) were flexible. The loop length column collects the lengths of these loops. ***: 1dle has residues with insertion codes in the loops, leading to a longer loop than is obvious. The name column identifies the name and function of the protein as listed in the PDB.本表格收集了本研究中所用复合物的结构参数，以及锚点排布等选定参数。PDB（Protein Data Bank，蛋白质数据库）列用于标识对应结构。chains（链）列用于标识PDB文件中所使用的复合物——部分PDB文件的不对称单元中包含多个复合物。*：2obg并非以异二聚体形式结晶，其以融合蛋白形式表达，最终以无限结构域交换聚合物的形式结晶[24]。resolution（分辨率）列标注了该晶体结构的报道分辨率，所有数值均合理。dimer type（二聚体类型）列用于标识二聚体的类型。**：1dle对应的是晶体二聚体而非生物学功能性二聚体，因此可作为弱相互作用研究的优质测试样本。SASA（Solvent Accessible Surface Area，溶剂可及表面积）列标注了蛋白质界面的掩埋面积。anchor（锚点）与chain（链）列共同用于标识作为锚点的残基。loop（环区）列用于标识与锚点处于同一条链上的柔性残基。loop length（环区长度）列统计了上述环区的长度。***：1dle的环区残基带有插入编码，导致其环区长度比直观观察到的更长。name（名称）列标注了PDB数据库中记录的蛋白质名称与功能。