circASCOR enhances platinum resistance in ovarian cancer

We have employed a snRNA-seq to study circRNA ASCOR in ovarian cancer cisplatin resistance. Overall design: The expression level of circASCOR was detected by RT-qPCR, and samples were divided into high-expression and low-expression groups according to the expression level and analyzed using snRNA-seq.

本研究采用单细胞核RNA测序（snRNA-seq）技术，针对环状RNA（circRNA）ASCOR在卵巢癌顺铂耐药中的相关功能展开研究。实验设计概况：通过逆转录实时定量聚合酶链反应（RT-qPCR）检测circASCOR的表达水平，依据表达量将样本分为高表达组与低表达组，随后利用snRNA-seq对两组样本进行测序分析。