Additional file 1: Table S1. of The abundance of cis-acting loci leading to differential allele expression in F1 mice and their relationship to loci harboring genes affecting complex traits
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RNA-Seq depth in forebrain and kidney of reciprocal F1 crosses. Tabl S2. SNVs detected by exome sequencing (Exome) or/and Sanger mouse SNVs database (Sanger) in three inbred mouse strains. Table S3. List of imprinted genes containing SNVs, which were observed with 8 reads in forebrain RNAseq. Table S4. Statistically significant evidence of DAE ratios diverging from 1:1 observed in reciprocal crosses. Table S5. Phenotype-related QTLs reported in BxD RI mice or F2 mice derived from B6 and DBA. Table S6. Genes at phenotype QTLs have DAE QTLs. Table S7. Genes implicated as phenotypic QTLs showing no DAE in (A) forebrain and (B) kidney of B6/DBA2 F1 mice. Table S8. 16 Imprinted genes (including four imprinted non-coding RNAs) detected by brain RNA-Seq of B6/CASTF1. Table S9. Primers for differentially allelic expression analysis or quantitative PCR. Table S10. Quantitative PCR verification of 10 DAE QTLs in parental strains, C57BL/6J and 129S1/SvlmJ. (ZIP 639 kb)
正反交F1杂交小鼠前脑与肾脏组织的RNA测序(RNA-Seq)测序深度数据
表S2:3个近交小鼠品系中,通过外显子组测序(Exome)或/和Sanger小鼠单核苷酸变异数据库(Sanger)检测得到的单核苷酸变异(SNVs)信息
表S3:携带单核苷酸变异且在前脑RNA测序中被观测到覆盖8条测序读段的印记基因列表
表S4:正反交实验中观测到的、与1:1表达比例存在显著偏离的差异等位基因表达(Differential Allelic Expression, DAE)比值的统计学显著证据
表S5:已报道的、在BxD重组近交系(Recombinant Inbred, RI)小鼠或由B6与DBA杂交培育的F2小鼠中存在的表型相关数量性状位点(Quantitative Trait Locus, QTL)
表S6:位于表型相关数量性状位点区域内、同时携带差异等位基因表达数量性状位点的基因列表
表S7:被认定为表型相关数量性状位点候选基因、且在B6/DBA2 F1小鼠的(A)前脑与(B)肾脏组织中未表现出差异等位基因表达的基因
表S8:通过B6/CAST F1小鼠脑组织RNA测序检测得到的16个印记基因(包含4个印记非编码RNA)
表S9:用于差异等位基因表达分析或定量PCR的引物序列
表S10:在亲本品系C57BL/6J与129S1/SvlmJ中,针对10个差异等位基因表达数量性状位点开展定量PCR验证的相关数据(压缩包大小:639 KB)
创建时间:
2016-12-15



