Transcriptome of mouse renal cortices without or with acute kidney injury, and without or with renal tubular epithelial cell-specific deficiency of the glucocorticoid receptor

Microarray expression data of the renal cortex of mice without or with myoglobinuric acute kidney injury, and without or with renal tubular epithelial cell-specific deficiency of the glucocorticoid receptor RNA was extracted from the renal cortex of healthy mice and of mice 24 hours after induction of myoglobinuric acute kidney injury (intramuscular injection of glycerol). Mice with tubular epithelial cell-specific deficiency of the glucocorticoid receptor (genotype Pax8-Cre;nr3c1 flox/flox) were compared to controls (genotype nr3c1 flox/flox).

本数据集涵盖伴或不伴肌红蛋白性急性肾损伤（myoglobinuric acute kidney injury）、伴或不伴肾小管上皮细胞特异性糖皮质激素受体RNA缺陷（renal tubular epithelial cell-specific deficiency of the glucocorticoid receptor RNA）的小鼠肾皮质的微阵列基因表达数据（Microarray expression data）。实验样本提取自健康小鼠，以及经肌内注射甘油（intramuscular injection of glycerol）诱导肌红蛋白性急性肾损伤24小时后的小鼠肾皮质。本研究将携带肾小管上皮细胞特异性糖皮质激素受体RNA缺陷的小鼠（基因型为Pax8-Cre;nr3c1 flox/flox）与对照小鼠（基因型为nr3c1 flox/flox）进行对比分析。